CANINE ANGIOSTRONGYLOSIS: RECENT ADVANCES IN DIAGNOSIS, PREVENTION, AND TREATMENT



The DNMT3A PWWP domain is essential for the normal DNA methylation landscape in mouse somatic cells and oocytes.

DNA methylation at CG sites is important for gene regulation and embryonic development.In mouse oocytes, de novo CG methylation requires preceding transcription-coupled histone mark H3K36me3 and is mediated by a DNA methyltransferase DNMT3A.DNMT3A has a PWWP domain, which recognizes H3K36me2/3, and heterozygous mutations in this domain, including D

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Tailoring a traditional Chinese medicine prescription for complex diseases: A novel multi-targets-directed gradient weighting strategy

Traditional Chinese medicine (TCM) sweet nothings acai bowl exerts integrative effects on complex diseases owing to the characteristics of multiple components with multiple targets.However, the syndrome-based system of diagnosis and treatment in TCM can easily lead to bias because of varying medication preferences among physicians, which has been a

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